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- Multitarget antibacterial drugs: An effective strategy to combat . . .
Multitarget drugs refer to a single drug acting on multiple biological targets in one or more pathways The research model of single-target drugs has inherent flaws: it can only regulate one specific step in the disease process, while most diseases are not caused by a single gene or target
- Molecular hybridization: a powerful tool for multitarget drug . . . - PubMed
The article discusses the design strategies and target selection for a multitarget polypharmacology approach to treat various diseases, including cancer, Alzheimer's disease, cardiac arrhythmia, endometriosis, and inflammatory diseases
- Automated design of multi-target ligands by generative deep learning
Chemical language models are deep learning models trained with molecules in string representation They enable data-driven de novo design of molecules with tailored features Here, the authors
- Frontiers | Editorial: Multi-target drug discovery and design for . . .
Nonetheless, the development of reliable computational models and experimental systems, particularly those integrating omics data and artificial intelligence, remains essential for accurately predicting multitarget effects
- Polypharmacology: The science of multi-targeting molecules
Histone deacetylase inhibitors as multitarget ligands: new players in Alzheimer’s disease drug discovery?
- GitHub - Smorodov Multitarget-tracker: Multiple Object Tracker, Based . . .
Multiple Object Tracker, Based on Hungarian algorithm + Kalman filter - Smorodov Multitarget-tracker
- Multitarget Compounds Designed for Alzheimer, Parkinson, and . . . - MDPI
Multitarget drugs are molecules with the ability to act simultaneously on different targets at the same time, and they have been evaluated in the last decade as a powerful tool in the development of promising therapeutics for neurodegenerative diseases
- Recent Insights in Multi‐Target Drugs in . . . - Chemistry Europe
Multitarget drugs exemplify polypharmacology, offering the advantage of simultaneous modulation of multiple targets and pathways involved in disease progression
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