Transcriptional Regulation: Molecules, Involved Mechanisms, and . . . Transcriptional regulation is a critical biological process that allows the cell or an organism to respond to a variety of intra- and extra-cellular signals, to define cell identity during development, to maintain it throughout its lifetime, and to coordinate cellular activity
Organization and regulation of gene transcription - Nature The latter include factors that are required for co-transcriptional pre-mRNA processing (in particular, splicing and 3′ processing), and factors for chromatin remodelling and modification