Introduction - MEME Suite The MEME Suite Motif-based sequence analysis tools Development of the MEME Suite was funded by grant R01 GM103544 from the National Institutes of Health
MEME - MEME Suite MEME represents motifs as position-dependent letter-probability matrices that describe the probability of each possible letter at each position in the pattern Individual MEME motifs do not contain gaps Patterns with variable-length gaps are split by MEME into two or more separate motifs
Overview - MEME Suite The MEME Suite allows the biologist to discover novel motifs in collections of unaligned nucleotide or protein sequences, and to perform a wide variety of other motif-based analyses The MEME Suite supports motif-based analysis of DNA, RNA and protein sequences You can also us it with sequences over novel sequence alphabets that you define
Installation - MEME Suite The MEME Suite Motif-based sequence analysis tools Installation of the MEME Suite The MEME Suite consists of several command line programs and an optional web server Installing the command line programs is very straight-forward See the 'Quick Install' links below to get started
STREME - MEME Suite STREME writes its output to files in a directory named streme_out, which it creates if necessary You can change the output directory using the --o or --oc options The directory will contain: streme html - an HTML file that provides the results in an interactive, human-readable format streme txt - a text file containing the motifs discovered by STREME in MEME format sequences tsv - a TSV (tab
Download Releases - MEME Suite Notice The scheduled system maintenance has been completed and the site is avilable for use Thank you for your patience
MEME - Submission form MEME discovers novel, ungapped motifs (recurring, fixed-length patterns) in your sequences (sample output from sequences) MEME splits variable-length patterns into two or more separate motifs See this Manual for more information of the documentation (button above) for more information on this tool
Motif Databases - MEME Suite [Click a category to show its available databases Within a category click a database to see details ]
MEME Suite Releases MEME Suite Software These releases include the complete source code of the MEME Suite which can be compiled to run on OS X or Linux They can be compiled on a Windows PC using a virtual machine (running Linux) or the Windows Subsystem for Linux
FIMO - MEME Suite FIMO scans a set of sequences for individual matches to each of the motifs you provide (sample output for motifs and sequences) The name FIMO stands for 'Find Individual Motif Occurrences' The program searches a set of sequences for occurrences of known motifs, treating each motif independently Motifs must be in MEME Motif Format The web version of FIMO also allows you to type in motifs in