Divalproex Sprinkle: Package Insert Prescribing Info Divalproex sodium delayed-release capsules, USP (sprinkle) contain specially coated particles of divalproex sodium equivalent to 125 mg of valproic acid in a hard gelatin capsule
depakote-sprinkle-capsules - Food and Drug Administration Depakote Sprinkle Capsules may be added to the patient's regimen at a dosage of 10 to 15 mg kg day The dosage may be increased by 5 to 10 mg kg week to achieve optimal clinical response
Depakote® (divalproex sodium) dosing for epilepsy Consideration may be given at the clinician's discretion to increase the patient's total daily doses of Depakote to the next higher dosage before converting to the appropriate total daily dose of Depakote ER
How to Switch Between Valproate Formulations? - Psychiatry Education Forum Valproate is available in following different formulations: Valproic acid liquid Divalproex sodium sprinkle capsules Divalproex sodium delayed-release tablets Divalproex sodium enteric-coated tablets Divalproex sodium ER (Extended Release)
Guidance on Converting from Divalproex Sodium (Depakote) to Valproic . . . Therapeutic substitution, where one drug is replaced with a less expensive drug, is one tool to help with this One substitution we’re occasionally asked about is using valproic acid (VPA) (Depakene) in place of divalproex sodium (Depakote) VPA costs about half as much as divalproex in most cases 1
label - accessdata. fda. gov This reduction may be started at initiation of Depakote Sprinkle Capsules therapy, or delayed by 1 to 2 weeks if there is a concern that seizures are likely to occur with a reduction
Anti-Convulsants - GlobalRPH Conversion from DEPAKOTE to DEPAKOTE ER : In adult patients and pediatric patients 10 years of age or older with epilepsy previously receiving DEPAKOTE, DEPAKOTE ER should be administered once-daily using a dose 8 to 20% higher than the total daily dose of DEPAKOTE (see table below)